Table 4 Genotypic distribution frequencies of codon 392 in exon 7 of estrogen receptor-β gene and selected demographic characteristics and major risk factors
Characteristic | 002 % | 01b% | 11c % | Test result |
|---|---|---|---|---|
BMI (kg/m 2 ) | ||||
</= 18.5 | 80.0 | 20.0 | - | χ2 = 0.144 P = 0.705 |
18.5-24.9 | 91.2 | 7.0 | 1.8 | |
25-29.9 | 90.9 | 9.1 | - | |
> 30 | 87.9 | 9.1 | 3.0 | |
Total | 90.0 | 8.7 | 1.3 | |
Onset age of breast cancer (years) | ||||
</= 40 | 91.7 | 8.3 | - | χ2 = 0.959 P = 0.328 |
> 40 | 89.2 | 8.8 | 2.0 | |
Total | 90.0 | 8.7 | 1.3 | |
Family history of breast cancer | ||||
First-degree family affected | 36.8 | 52.6 | 10.5 | χ2 = 27.645 P = 0.001 |
Not affected | 97.7 | 2.3 | - | |
Total | 90 | 8.7 | 1.3 | |
Lymph node metastases | ||||
Yes | 60.9 | 30.4 | 8.7 | χ2 = 17.314 P = 0.001 |
No | 95.3 | 4.7 | - | |
Total | 90.0 | 8.7 | 1.3 | |
ER expression in breast cancer tissue | ||||
Positive | 80.0 | 15.0 | 5.0 | χ2 = 4.799 P = 0.028 |
Negative | 94.6 | 5.4 | - | |
Not studied | 88.9 | 11.1 | - | |
Total | 90.0 | 8.7 | 1.3 |