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Table 2 Estimated haplotype frequencies in NOS1AP

From: Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls

Haplotype block

Frequency (%)

P values

 

SCZ

ASD

Control

SCZ vs. control

ASD vs. control

1 (rs10918776- rs10800405)

     

   CT

0.55

0.48

0.48

0.23

0.98

   TC

0.45

0.52

0.52

0.23

0.98

2 (rs3751285 - rs3751285)

     

   AG

0.56

0.46

0.59

0.28

0.45

   GT

0.23

0.28

0.28

0.40

0.96

   AT

0.11

0.17

0.13

0.74

0.33

3 (rs348624 - rs1964052)

     

   CC

0.89

0.85

0.91

0.50

0.07*

   TT

0.11

0.15

0.08

0.50

0.07*

4 (rs164146 - rs164147)

     

   GC

0.83

0.84

0.84

0.71

0.99

   CA

0.18

0.16

0.16

0.71

0.99

  1. * P = 0.53 when 10000 permutations where simulated. Significant P values (<0.05) are in bold. Abbreviations: ASD: autism spectrum disorders, SCZ: schizophrenia.