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Table 1 Allele and genotype frequencies of frequent polymorphisms in NOS1AP*

From: Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls

Polymorphisms# Location Number of alleles (frequency) Number of Genotype (frequency)
   Allele 1 Allele 2 P (df = 1) 11 12 22 P (df = 2)
rs10918776 Intron 2 G C      
   SCZ   100 (0.77) 32 (0.23) 0.46 42 22 5 0.57§
   ASD   117 (0.72) 45 (0.28) 0.06 39 37 4 0.06§
   Controls   142 (0.80) 34 (0.20)   57 28 3  
rs10800405 Intron 3 C G      
   SCZ   91 (0.76) 31 (024) 0.92 37 25 3 0.98§
   ASD   102 (0.74) 36 (0.26) 0.63 34 33 1 0.60§
   Controls   113 (0.77) 35 (0.23)   43 29 3  
rs347306 and rs347307 Intron 5 C and T T and C      
   SCZ   74 (0.56) 60 (0.44) 0.19 20 38 12 0.23
   ASD   82 (0.52) 76 (0.48) 0.98 17 41 20 0.46
   Controls   87 (0.52) 81 (0.48)   15 54 18  
rs3751285 Intron 6 A G      
   SCZ   68 (0.77) 20 (0.33) 0.35 28 12 4 0.32§
   ASD   97 (0.71) 39 (0.29) 0.96 34 27 6 0.97
   Controls   106 (0.72) 42 (0.28)   39 31 6  
rs3751284 Exon 6 C T      
   SCZ   58 (0.66) 30 (0.34) 0.35 20 18 6 0.45
   ASD   75 (0.55) 61 (0.45) 0.32 20 34 13 0.69
   Controls   88 (0.60) 60 (0.40)   26 39 11  
rs905721 Intron 8 C T      
   SCZ   96 (0.70) 42 (0.30) 0.10 33 30 6 0.22
All SCZ   353 (0.62) 213 (0.38) 0.92 114 125 44 0.86
   ASD   104 (0.66) 54 (0.34) 0.33 31 41 6 0.02
All ASD   360 (0.64) 198 (0.36) 0.41 115 130 34 0.27
   Controls   98 (0.65) 52 (0.35)   37 24 14  
All controls   309 (0.62) 189 (0.38)   102 105 42  
rs348624 and rs1964052 Exon 9 and intron 9 C and C T and T      
   SCZ   121 (0.89) 15 (0.11) 0.48 54 13 1 0.49§
All SCZ   500 (0.87) 74 (0.13) 0.34 218 63 6 0.50
   ASD   132 (0.85) 24 (0.15) 0.07 55 18 3 0.07§
All ASD   472 (0.86) 74 (0.14) 0.22 206 60 7 0.39
   Controls   137 (0.91) 13 (0.09)   62 13 0  
All controls   283 (0.89) 34 (0.11)   128 29 2  
rs164146 and rs164147 Exon 10 G and C C and A      
   SCZ   104 (0.83) 22 (0.17) 0.71 43 18 2 0.73§
   ASD   133 (0.84) 25 (0.16) 0.99 56 20 2 0.91§
   Controls   128 (0.84) 24 (0.16)   57 23 1  
  1. *Polymorphisms included have a minor allele frequency above 0.05. # Markers are listed from centromere au telomere. § Fischer exact Test. Significant P values (<0.05) are in bold. Abbreviations: ASD: autism spectrum disorders, SCZ: schizophrenia.