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Table 2 Associations of the FTO rs9939609 variant with anthropometric and metabolic parameters (mean ± SE).

From: The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China

 

FTO rs9939609 genotypea

  
 

TT

TA

AA

p-value for trenda

Estimated change unit per A allele (95% CI)a

All(n)

2718

724

61

  

Height (cm)

152.3 ± 0.1

152.3 ± 0.3

153.6 ± 1.0

0.39

0.24 ((-0.33)-0.81)

Weight (kg)

51.9 ± 0.2

54.0 ± 0.5

55.6 ± 1.7

3.29 × 10-5 b

2.01 (1.06-2.96)

Body mass index (kg/m2)

21.7 ± 0.1

22.5 ± 0.2

23.0 ± 0.6

1.39 × 10-6 b

0.79 (0.47-1.10)

Body mass index-standard deviation score

1.15 ± 0.03

1.40 ± 0.05

1.61 ± 0.19

3.76 × 10-6 b

0.25 (0.14-0.35)

Waist circumference (cm)

72.0 ± 0.2

73.7 ± 0.4

75.0 ± 1.4

2.26 × 10-5 b

1.73 (0.93-2.54)

Waist-to-Height Ratio

0.472 ± 0.001

0.484 ± 0.002

0.488 ± 0.009

1.94 × 10-5 b

0.01 (0.006-0.015)

Fat mass percentage (%)

24.1 ± 0.1

25.4 ± 0.3

25.6 ± 1.0

9.75 × 10-5 b

1.16 (0.57-1.74)

Birth weight (g)

3358 ± 11

3345 ± 20

3342 ± 70

0.54

-12 ((-51)-27)

Systolic blood pressure (mmHg)

107.1 ± 0.2

109.2 ± 0.5

108.7 ± 1.6

1.41 × 10-4 b [0.14c]

1.7 (0.8-2.6) [0.6((-0.2)-1.3)c]

Diastolic blood pressure (mmHg)

67.6 ± 0.2

68.4 ± 0.3

69.3 ± 1.2

0.01b [0.63c]

0.8 (0.2-1.5)[0.1 ((-0.5)-0.8)c]

Total cholesterol (mmol l-1)

4.09 ± 0.02

4.10 ± 0.03

3.99 ± 0.10

0.69

-0.01 ((-0.07)-0.05)

Triglycerides (mmol l-1)

1.03 ± 0.01

1.04 ± 0.02

1.03 ± 0.07

0.67

0.01 ((-0.03)-0.05)

HDL-cholesterol (mmol l-1)

1.41 ± 0.01

1.38 ± 0.01

1.42 ± 0.04

0.11

-0.02 ((-0.04)-0.01)

LDL-cholesterol (mmol l-1)

2.54 ± 0.01

2.58 ± 0.03

2.41 ± 0.10

0.83

0.01 ((-0.05)-0.06)

Fasting plasma glucose (mmol l-1)

5.09 ± 0.01

5.10 ± 0.02

5.04 ± 0.08

0.98

0.001 ((-0.04)-0.04)

  1. a Adjusted for age and gender.
  2. b Indicates that the p-value remains significant after a false discovery rate control.
  3. c Adjusted for age, gender and body mass index.