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Table 2 Associations of the FTO rs9939609 variant with anthropometric and metabolic parameters (mean ± SE).

From: The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China

  FTO rs9939609 genotypea   
  TT TA AA p-value for trenda Estimated change unit per A allele (95% CI)a
All(n) 2718 724 61   
Height (cm) 152.3 ± 0.1 152.3 ± 0.3 153.6 ± 1.0 0.39 0.24 ((-0.33)-0.81)
Weight (kg) 51.9 ± 0.2 54.0 ± 0.5 55.6 ± 1.7 3.29 × 10-5 b 2.01 (1.06-2.96)
Body mass index (kg/m2) 21.7 ± 0.1 22.5 ± 0.2 23.0 ± 0.6 1.39 × 10-6 b 0.79 (0.47-1.10)
Body mass index-standard deviation score 1.15 ± 0.03 1.40 ± 0.05 1.61 ± 0.19 3.76 × 10-6 b 0.25 (0.14-0.35)
Waist circumference (cm) 72.0 ± 0.2 73.7 ± 0.4 75.0 ± 1.4 2.26 × 10-5 b 1.73 (0.93-2.54)
Waist-to-Height Ratio 0.472 ± 0.001 0.484 ± 0.002 0.488 ± 0.009 1.94 × 10-5 b 0.01 (0.006-0.015)
Fat mass percentage (%) 24.1 ± 0.1 25.4 ± 0.3 25.6 ± 1.0 9.75 × 10-5 b 1.16 (0.57-1.74)
Birth weight (g) 3358 ± 11 3345 ± 20 3342 ± 70 0.54 -12 ((-51)-27)
Systolic blood pressure (mmHg) 107.1 ± 0.2 109.2 ± 0.5 108.7 ± 1.6 1.41 × 10-4 b [0.14c] 1.7 (0.8-2.6) [0.6((-0.2)-1.3)c]
Diastolic blood pressure (mmHg) 67.6 ± 0.2 68.4 ± 0.3 69.3 ± 1.2 0.01b [0.63c] 0.8 (0.2-1.5)[0.1 ((-0.5)-0.8)c]
Total cholesterol (mmol l-1) 4.09 ± 0.02 4.10 ± 0.03 3.99 ± 0.10 0.69 -0.01 ((-0.07)-0.05)
Triglycerides (mmol l-1) 1.03 ± 0.01 1.04 ± 0.02 1.03 ± 0.07 0.67 0.01 ((-0.03)-0.05)
HDL-cholesterol (mmol l-1) 1.41 ± 0.01 1.38 ± 0.01 1.42 ± 0.04 0.11 -0.02 ((-0.04)-0.01)
LDL-cholesterol (mmol l-1) 2.54 ± 0.01 2.58 ± 0.03 2.41 ± 0.10 0.83 0.01 ((-0.05)-0.06)
Fasting plasma glucose (mmol l-1) 5.09 ± 0.01 5.10 ± 0.02 5.04 ± 0.08 0.98 0.001 ((-0.04)-0.04)
  1. a Adjusted for age and gender.
  2. b Indicates that the p-value remains significant after a false discovery rate control.
  3. c Adjusted for age, gender and body mass index.