No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families

Table 4 P values of QTDT analyses for FRZB gene and BMD in female-offspring nuclear families

	rs6433993	rs409238	rs288324	rs4666865
Tests of population stratification
Lumbar spine BMD	0.2597	0.7082	0.7210	0.6797
Total hip BMD	0.1201	0.4474	0.6278	0.3498
Femoral neck BMD	0.9553	0.5299	0.8853	0.5387
Test of total association
Lumbar spine BMD	0.5910	0.9239	0.8353	0.3077
Total hip BMD	0.7237	0.6503	0.2945	0.7763
Femoral neck BMD	0.4555	0.2779	0.1819	0.9844
Test of within-family association
Lumbar spine BMD	0.5047	0.7121	0.8470	0.8338
Total hip BMD	0.1345	0.3765	0.3300	0.5350
Femoral neck BMD	0.6584	0.9779	0.5681	0.6117
p 1000 permutations of within-family association
Lumbar spine BMD	0.3950	0.6670	0.7830	0.8090
Total hip BMD	0.1110	0.3520	0.2680	0.5170
Femoral neck BMD	0.6440	0.9780	0.5990	0.6650

ISSN: 1471-2350