Category
|
Type
|
Count
|
Percent
|
|---|
False Positive Calls | Simple False Positives | 8 | 44% |
False Positive Calls | Reflected Duplication | 8 | 44% |
False Positive Calls | Reflected Overlap | 2 | 11% |
False Positive Calls | Total | 18 | 100% |
Missed Calls | Too Close | 14 | 58% |
Missed Calls | Overlapping Intervals | 3 | 13% |
Missed Calls | Ambiguous | 4 | 17% |
Missed Calls | Chromosome Ends | 3 | 13% |
Missed Calls | Total | 24 | 100% |
- Analysis of false positive calls and false negatives (crossovers that were missed by the algorithm). Simple false positive refers to false positive calls that were not a result of comparisons to one parent reflecting events occurring in the other parent. Reflected Duplication false positive calls were predicted crossovers called in both parents at the same site, when there was only recombination in one parent. Reflected Overlap refers to erroneous calls being the result of intervals overlapping as a result of reflected events. Too Close refers to a recombination inherited by one sibling being very close to a second recombination inherited by a different sibling, but transmitted from the same parent. Overlapping Intervals that resulted in false positive calls often also resulted the inability to make the correct call. Ambiguous calls occurred when a call was made at the same region in both parents, thus the parent of origin cannot be phased; ambiguous calls were reported by the algorithm, but were not counted as having been detected. Chr Ends refers to actual recombination sites that were within ~250 Kb of the ends of the chromosomes; this algorithm cannot resolve crossovers that occurred in this region.
