Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study

BMC Medical Genetics

Table 2 Allele frequencies and summary statistics for significant SNPs before adjustment for multiple testing

Gene¹	SNP	MA	MAF patients	MAF controls	OR	L95	U95	p
OPTN	rs10796021	C	0.471	0.405	1.316	1.022	1.695	0.033
OPTN	rs3829923	T	0.375	0.444	0.768	0.602	0.980	0.034
OPTN	rs7921853	T	0.498	0.415	1.356	1.069	1.721	0.012
OPTN	rs765884	C	0.315	0.224	1.558	1.179	2.059	1.838 × 10^-3
MFN1	rs2111534	A	0.384	0.450	0,748	0.583	0.960	0.023
MFN2	rs873458	G	0.496	0.432	1.292	1.019	1.639	0.035
MFN2	rs2295281	C	0.493	0.423	1.327	1.044	1.687	0.021
MFN2	rs11588779	T	0.221	0.282	0.721	0.547	0.950	0.020
PARL	rs1000002	C	0.539	0.437	1.478	1.091	2.002	0.012
PARL	rs1402003	G	0.464	0.368	1.471	1.079	2.006	0.015

¹Refers to the gene for which LD blocks were calculated. MA, minor allele; MAF, minor allele frequency; OR, odds ratio; L95, confidence interval 95% lower bound; U95, confidence interval 95% upper bound

ISSN: 1471-2350