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Table 4 Genotypes and alleles distribution for NOD1 variants in UC and Controls

From: Frequency of single nucleotide polymorphisms in NOD1gene of ulcerative colitis patients: a case-control study in the Indian population

 

total

Wild-type

Heterozygous

Homozygous

Minor allele frequency

OR1

95% CI1

P 2

      

UC vs. control

Patients

        

4644T>A

W219R

       

UC

95

61(64.2)

19(20.0)

15(15.8)

26

   

Controls

102

89(87.3)

7(6.9)

6(5.9)

9

3.960

1.569-9.995

0.002*

4773delG

        

UC

95

72(75.8)

15(15.8)

8(8.4)

16

   

Controls

102

87(85.3)

10(9.8)

5(4.9)

10

1.853

0.900-3.812

0.091

4785G>A

E266K

       

UC

95

53(55.8)

27(28.4)

15(15.8)

30

   

Controls

102

68(66.7)

24(23.5)

10(9.8)

22

1.443

0.748-2.784

0.272

5035T>C

L349P

       

UC

95

74(77.9)

12(12.6)

9(9.5)

16

   

Controls

102

55(53.9)

29(28.4)

18(17.6)

32

0.308

0.144-0.656

0.002*

5098T>G

L370R

       

UC

95

55(57.9)

19(20.0)

21(22.1)

32

   

Controls

102

67(65.7)

24(23.5)

11(10.8)

23

2.326

1.033-5.238

0.039*

  1. 1ORs and probability values at 95% CI for disease status are shown.
  2. 2p-values were calculated with the Fisher's Exact test when comparing controls and UC patients.
  3. P values refer to the UC vs. controls. *showing significant P value.