IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease

Table 2 Single-marker association of IL23R to IBD, celiac disease and psoriasis

			rs1004819*T		rs10489629*C		rs2201841*C		rs11465804*G		rs11209026*A		rs1343151*C		rs10889677*A		rs11209032*A
		N (cases/controls)	p-value	OR	p-value	OR	p-value	OR	p-value	OR	p-value	OR	p-value	OR	p-value	OR	p-value	OR
A	SWE IBD [UC&CD]	773/280	0.004	1.38	0.006	0.76	0.054		0.002	0.42	0.003	0.45	0.014	1.30	0.088		0.130
	SWE IBD UC	461/280	0.013	1.36	0.002	0.72	0.044	1.27	0.003	0.42	0.007	0.43	0.012	1.34	0.059		0.111
	SWE IBD CD	337/280	0.006	1.43	0.049	0.80	0.188		0.022	0.47	0.038	0.51	0.039	1.29	0.323		0.312
B	HUN CEL	610/269	0.273		0.665		0.444		0.220		0.390		0.492		0.335		0.546
	FIN CEL	460/292	0.400		0.773		0.401		0.874		0.503		0.247		0.499		0.634
	ITA CEL	138/194	0.803		0.324		0.390		0.753		0.778		0.570		0.334		0.491
	ALL CEL	1208/750	0.524		0.865		0.846		0.279		0.677		0.399		0.849		0.424
C	FIN PSOR	250/292	0.853		0.203		0.619		0.186		0.357		0.776		0.808		0.582

Association of SNPs in IL23R to inflammatory bowel disease (IBD), psoriasis (PSOR) and celiac disease (CEL) in cohorts from Sweden (SWE), Finland (FIN), Hungary (HUN) and Italy (ITA). Association to ulcerative colitis [UC] and Crohn's disease [CD] in the Swedish IBD (A); to celiac disease in the Finnish, Hungarian and Italian populations or combined material (B); and to psoriasis in the Finnish population (C). OR refers to odds ratios. Statistically significant p-values (p < 0.05) are highlighted in bold; p-values lower than 10^-3 are highlighted in bold and underlined. Detailed data are shown in Additional file 3.

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