Figure 2
From: New mutations in the PKD1 gene in Czech population with autosomal dominant polycystic kidney disease
The graphic alignment of putative causal missense mutations in PKD1 gene. Multiple sequence alignment of protein sequences was performed with distant species: Human - sp|P98161-3|PKD1_HUMAN Isoform 3 of Polycystin-1; Canis lupus familiaris - ref|NP_001006651.1| polycystin 1; Mus musculus - ref|NP_038658.2| polycystin 1; Gallus gallus - ref|XP_414854.2| PREDICTED: similar to polycystin 1; Xenopus laevis - gb|AAT77543.1| polycystic kidney disease protein 1 precursor; Takifugu rubripes - gb|AAB86683.1| unknown; Amphioxus - Branchiostoma floridae ref|XP_002202413.1| hypothetical protein BRAFLDRAFT_64810; Echinoid - Strongylocentrotus purpuratus ref|XP_001194831.1| PREDICTED: similar to receptor for egg jelly 4;Sea anemone - Nematostella vectensis ref|XP_001640030.1| predicted protein; Placozoa - Trichoplax adhaerens ref|XP_002110052.1| hypothetical protein TRIADDRAFT_53596. The positions of putative missense mutations are marked by red arrows.