Table 3 Genotypic and allelic association analysis of vitamin D receptor single-nucleotide polymorphisms in the Chinese asthma study.
SNPs ID | Controls (n = 523) | Asthmatics (n = 567) | OR (95% CI) | Pvalue | Genotype | Controls (n = 523) | Asthmatics (n = 567) | Pvalue |
|---|---|---|---|---|---|---|---|---|
rs2228570 | Â | Â | Â | Â | CC | 152 (0.29) | 193 (0.34) | Â |
C | 569 (0.54) | 644 (0.57) | 1.00 | Â | CT | 265 (0.51) | 258 (0.46) | Â |
T | 477 (0.46) | 490 (0.43) | 1.10 (0.93–1.30) | 0.261 | TT | 106 (0.20) | 116 (0.20) | 0.161 |
rs3782905 | Â | Â | Â | Â | CC | 378 (0.72) | 415 (0.73) | Â |
C | 895 (0.85) | 972 (0.86) | 1.00 | Â | CG | 139 (0.27) | 142 (0.25) | Â |
G | 132 (0.15) | 162 (0.14) | 0.88 (0.69–1.13) | 0.920 | GG | 6 (0.01) | 10 (0.02) | 0.754 |
rs1544410 | Â | Â | Â | Â | GG | 472 (0.90) | 515 (0.91) | Â |
G | 995 (0.95) | 1079 (0.95) | 1.00 | Â | GA | 51 (0.01) | 49 (0.08) | Â |
A | 51 (0.05) | 55 (0.05) | 1.00 (0.68–1.48) | 0.977 | AA | 0 (0.00) | 3 (0.01) | 0.208 |
rs7975232 | Â | Â | Â | Â | CC | 247 (0.47) | 310 (0.55) | Â |
C | 710 (0.68) | 837 (0.74) | 1.00 | Â | CA | 216 (0.41) | 217 (0.38) | Â |
A | 336 (0.32) | 297 (0.26) | 1.33 (1.10–1.60) | 0.002 | AA | 60 (0.12) | 40 (0.07) | 0.009 |
rs731236 | Â | Â | Â | Â | TT | 471 (0.90) | 510 (0.90) | Â |
T | 993(0.95) | 1073 (0.95) | 1.00 | Â | TC | 51 (0.09) | 53 (0.09) | Â |
C | 53(0.05) | 61(0.05) | 0.94 (0.64–1.37) | 0.446 | CC | 1 (0.01) | 4 (0.01) | 0.743 |