Table 5 Postnatal characteristics at 6, 12, and 24 months according to TCF7L2 rs7903146 genotype.
Generation R | CC (n = 1375) | CT (n = 1063) | TT (n = 237) | p-value# | |
|---|---|---|---|---|---|
6 months | Head circumference (SDS) | -0.02 (0.93) | -0.03 (0.89) | -0.06 (0.91) | 0.83 |
n = 2675 | Height (SDS) | 0.03 (0.91) | 0.03 (0.90) | 0.07 (0.93) | 0.81 |
Weight (SDS) | 0.41 (0.96) | 0.44 (0.95) | 0.54 (0.99) | 0.14 | |
12 months | Head circumference (SDS) | 0.00 (0.89) | -0.04 (0.94) | -0.03 (1.12) | 0.54 |
n = 2559 | Height (SDS) | -0.01 (0.90) | -0.05 (0.90) | -0.01 (0.90) | 0.70 |
Weight (SDS) | 0.18 (0.98) | 0.18 (0.99) | 0.24 (1.00) | 0.63 | |
24 months | Height (SDS) | -0.19 (0.93) | -0.21 (0.89) | -0.18 (0.87) | 0.82 |
n = 2445 | Weight (SDS) | -0.11 (0.99) | -0.13 (1.00) | -0.09 (0.96) | 0.87 |
SGA cohort | CC (n = 143) | CT (n = 107) | TT (n = 22) | ||
6 months | Head circumference (SDS) | -1.38 (0.92) | -1.36 (0.90) | -1.74 (1.04) | 0.41 |
n = 272 | Height (SDS) | -2.39 (1.37) | -2.43 (1.26) | -2.51 (1.55) | 0.93 |
Weight (SDS) | -2.18 (1.40) | -2.22 (1.26) | -2.37 (2.05) | 0.86 | |
12 months | Head circumference (SDS) | -1.21 (0.83) | -1.24 (0.88) | -1.72 (1.06) | 0.16 |
n = 268 | Height (SDS) | -2.25 (1.25) | -2.30 (1.06) | -2.30 (1.47) | 0.94 |
Weight (SDS) | -2.14 (1.41) | -2.25 (1.15) | -2.17 (1.89) | 0.82 | |
24 months | Head circumference (SDS) | -1.10 (0.82) | -1.13 (0.87) | -1.60 (1.06) | 0.20 |
n = 244 | Height (SDS) | -2.39 (1.24) | -2.47 (1.05) | -2.94 (1.04) | 0.20 |
Weight (SDS) | -2.19 (1.33) | -2.31 (1.21) | -3.06 (1.65) | 0.04 |