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Table 2 Genotypes and alleles distribution in patients with COPD and healthy smokers

From: Absence of association between SERPINE2genetic polymorphisms and chronic obstructive pulmonary disease in Han Chinese: a case-control cohort study

 

Case (%)

Control (%)

OR [95% CI]

P value

    

Allele test

Genotype test

HWE*

rs7579646

      

A

17.6

18.2

 

0.77

0.62

0.60

G/G

69.4

67.3

1.00

   

G/A

26.0

28.9

0.87 [0.62–1.23]

   

A/A

4.6

3.7

1.19 [0.56–2.56]

   

rs840088

      

T

43.0

43.3

 

0.91

0.91

0.22

C/C

33.3

33.8

1.00

   

C/T

47.4

45.8

1.05 [0.75–1.48]

   

T/T

19.3

20.3

0.96 [0.63–1.47]

   

rs3795877

      

C

13.0

12.9

 

0.96

0.97

0.57

T/T

75.8

76.2

1.00

   

T/C

22.3

21.8

1.03 [0.72–1.48]

   

C/C

1.8

2.0

0.92 [0.30–2.77]

   

rs6747096

      

G

13.0

12.9

 

0.96

0.97

0.57

A/A

75.8

76.2

1.00

   

A/G

22.3

21.8

1.03 [0.72–1.48]

   

G/G

1.8

2.0

0.92 [0.30–2.77]

   

rs3795879

      

A

13.0

12.9

 

0.96

0.97

0.57

G/G

75.8

76.2

1.00

   

G/A

22.3

21.8

1.03 [0.72–1.48]

   

A/A

1.8

2.0

0.92 [0.30–2.77]

   
  1. SNP = Single nucleotide polymorphism, OR = Odds ratio, CI = Confidence interval.
  2. *P-value from test for Hardy-Weinberg equilibrium in controls