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Table 4 Allele frequencies of the rs10061463 polymorphism in the three study cohorts for each phenotype

From: Lack of association of TIM3polymorphisms and allergic phenotypes

Cohort Phenotype Caucasian only Combined analysisa
   Frequency OR p cpc Frequency OR p cpc
CAPPS Asthma 0.18 0.85 0.6829 1.0000 0.16 1.00 1.0000 1.0000
  Atopy   0.78 0.3859 1.0000   0.80 0.4137 1.0000
  AHR   0.87 0.5528 1.0000   0.86 0.4967 1.0000
  Atopic Asthma   0.55 0.2218 1.0000   0.73 0.4904 1.0000
SAGE Asthma 0.17 1.10 0.7576 1.0000 0.15 1.13 0.6743 1.0000
  Atopy   1.18 0.5635 1.0000   1.14 0.6113 1.0000
  AHR   1.25 0.5045 1.0000   1.10 0.7576 1.0000
  Atopic Asthma   1.36 0.4319 1.0000   1.33 0.3972 1.0000
SLSJ/QC Asthma 0.25 0.97 0.7902 1.0000 0.25 0.97 0.7902 1.0000
  Atopy   1.03 0.8263 1.0000   1.03 0.8263 1.0000
  AHR   1.12 0.4232 1.0000   1.12 0.4232 1.0000
  Atopic Asthma   1.00 1.0000 1.0000   1.00 1.0000 1.0000
Combined analysisb Asthma 0.20 0.97 0.8149 1.0000 0.18 0.99 0.9542 1.0000
  Atopy   1.01 0.9526 1.0000   1.01 0.9542 1.0000
  AHR   1.07 0.5610 1.0000   1.05 0.6904 1.0000
  Atopic Asthma   0.99 0.9454 1.0000   1.02 0.8937 1.0000
  1. aCombined analysis of the Caucasian families with the non Caucasian families
  2. bCombined analysis of the three cohorts (CAPPS, SAGE and SLSJ/QC)
  3. ccorrected p value
  4. CAPPS – Canadian Asthma Primary Prevention Study Cohort; SAGE – Study of Asthma Genes and the Environment birth cohort; SLSJ/QC – Saguenay – Lac-St-Jean (SLSJ)/Québec City (QC) Familial Collection; AHR – airway hyperresponsiveness