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Table 4 Allele frequencies of the rs10061463 polymorphism in the three study cohorts for each phenotype

From: Lack of association of TIM3polymorphisms and allergic phenotypes

Cohort

Phenotype

Caucasian only

Combined analysisa

  

Frequency

OR

p

cpc

Frequency

OR

p

cpc

CAPPS

Asthma

0.18

0.85

0.6829

1.0000

0.16

1.00

1.0000

1.0000

 

Atopy

 

0.78

0.3859

1.0000

 

0.80

0.4137

1.0000

 

AHR

 

0.87

0.5528

1.0000

 

0.86

0.4967

1.0000

 

Atopic Asthma

 

0.55

0.2218

1.0000

 

0.73

0.4904

1.0000

SAGE

Asthma

0.17

1.10

0.7576

1.0000

0.15

1.13

0.6743

1.0000

 

Atopy

 

1.18

0.5635

1.0000

 

1.14

0.6113

1.0000

 

AHR

 

1.25

0.5045

1.0000

 

1.10

0.7576

1.0000

 

Atopic Asthma

 

1.36

0.4319

1.0000

 

1.33

0.3972

1.0000

SLSJ/QC

Asthma

0.25

0.97

0.7902

1.0000

0.25

0.97

0.7902

1.0000

 

Atopy

 

1.03

0.8263

1.0000

 

1.03

0.8263

1.0000

 

AHR

 

1.12

0.4232

1.0000

 

1.12

0.4232

1.0000

 

Atopic Asthma

 

1.00

1.0000

1.0000

 

1.00

1.0000

1.0000

Combined analysisb

Asthma

0.20

0.97

0.8149

1.0000

0.18

0.99

0.9542

1.0000

 

Atopy

 

1.01

0.9526

1.0000

 

1.01

0.9542

1.0000

 

AHR

 

1.07

0.5610

1.0000

 

1.05

0.6904

1.0000

 

Atopic Asthma

 

0.99

0.9454

1.0000

 

1.02

0.8937

1.0000

  1. aCombined analysis of the Caucasian families with the non Caucasian families
  2. bCombined analysis of the three cohorts (CAPPS, SAGE and SLSJ/QC)
  3. ccorrected p value
  4. CAPPS – Canadian Asthma Primary Prevention Study Cohort; SAGE – Study of Asthma Genes and the Environment birth cohort; SLSJ/QC – Saguenay – Lac-St-Jean (SLSJ)/Québec City (QC) Familial Collection; AHR – airway hyperresponsiveness