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Table 3 Genotype and allele frequencies of the SPINK5 SNPs in patients and controls

From: A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han Population

SNPs Genotype/allele Controls(%) Patients (%) Odds ratio (95% CI) P P*
-206 G>A AA 48 (6.75) 31 (4.63) 1.00   
  AG 243(34.18) 192 (28.70) 1.22(0.75–2.00)   
  GG 420(59.07) 446(66.67) 1.64(1.03–2.63) 0.01 0.05
  A 339 (23.84) 254(18.98) 1.00   
  G 1083(76.16) 1084(81.02) 1.34(1.11–1.60) 0.002 0.01
1103A>G AA 74(18.05) 92(21.80) 1.00   
  AG 201(49.02) 192(45.50) 0.77(0.53–1.11)   
  GG 135(32.93) 138(32.70) 0.82(0.56–1.21) 0.365  
  A 349(42.56) 376(44.55) 1.00   
  G 471(57.44) 468(55.45) 0.92(0.76–1.12) 0.429  
1156G>A GG 110(26.83) 111(26.30) 1.00   
  GA 201(49.02) 192(45.50) 0.95(0.68–1.32)   
  AA 99(24.15) 119(28.20) 1.19(0.82–1.73) 0.392  
  G 421(51.34) 414(49.05) 1.00   
  A 399(48.64) 430(50.95) 1.10(0.90–1.33) 0.352  
1258G>A GG 174(42.44) 169(40.05) 1.00   
  GA 199(48.54) 201(47.63) 1.04(0.78–1.39)   
  AA 37(9.02) 52(12.32) 1.45(0.90–2.34) 0.295  
  G 547(66.71) 539(63.86) 1.00   
  A 273(33.29) 305(36.14) 1.13(0.93–1.39) 0.236  
2475G>T GG 169(40.05) 191(46.59) 1.00   
  GT 201(47.63) 169(41.22) 0.97(0.74–1.32)   
  TT 52(12.32) 50(12.20) 1.07(0.69–1.65) 0.932  
  G 539(63.86) 551(67.20) 1.00   
  T 305(36.14) 269(32.80) 1.02(0.83–1.25) 0.835  
  1. P* indicates adjusting after Bonferroni correction