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Table 2 Age- and geographic location-adjusted odds ratios for invasive bacterial death with homozygosity at specific microsatellite markers in multivariable models restricted to cases of Gram positive sepsis, gram negative sepsis or including all invasive bacterial deaths combined.

From: Homozygosity and risk of childhood death due to invasive bacterial disease

  

Gram Negative

Gram Positive

Combined

Markers

Interaction

OR

95% CI

OR

95%CI

OR

95% CI

D7S486

 

1.02

0.16 – 6.53

    

D7S486

D16S423

40.7

4.28 – 387

    

D12S310

 

14.0

2.70 – 72.7

4.73

1.59–14.1

4.94

2.27 – 10.8

D13S158

 

6.11

1.45 – 25.8

  

4.66

1.92 – 11.3

D15S1007

 

7.28

1.89 – 28.1

    

D16S423

 

1.61

0.31 – 8.33

  

7.65

2.55 – 22.9

D9S164

infants

  

0.18

0.018 – 1.90

  

D9S164

children

  

1.65

0.249 – 10.9

  

D14S275

   

3.93

1.35 – 11.4

12.2

4.44 – 33.3

D14S275

D13S158

    

10.1

3.84 – 26.5

D16S3103

   

3.70

1.20 – 11.4

7.04

2.56 – 19.4

D16S3103

D16S423

    

10.2

4.10 – 25.2

  1. The table shows odds ratios, adjusted for age in 6 strata and for geographical location in 8 strata, of death due to all invasive bacterial disease, of death due to Gram negative invasive bacterial disease and of death due to Gram positive invasive bacterial disease, for homozygosity at microsatellite markers either alone or paired (where interactions were noted with LRT p values < 0.05). Variables excluded, with LRT p values = 0.05, in addition to sex and SOH, were markers d12s352, d14s261, d14s275, d16s3103 and d18s452 in the gram negative model, markers d13s158, d14s261, d14s280 and d16s423 in the gram positive model and markers d12s352, d14s261, d14s280 and d15s1007 in the combined model. Variables and interaction terms in the final models all had LRT p values < 0.02.