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Table 1 Nine microsatellites showing the strongest association between heterozygosity and mortality due to invasive bacterial disease.

From: Homozygosity and risk of childhood death due to invasive bacterial disease

Marker

OR

lower 95% CI

upper 95% CI

chi sq

p value

D12S310

2.86

1.68

4.86

15.420

0.000086

D12S352

2.66

1.64

4.31

16.194

0.000057

D13158

2.67

1.66

4.3

16.496

0.000049

D14S261

3.14

1.94

5.09

21.998

0.000003

D14S275

2.59

1.59

4.22

15.034

0.000106

D14S280

3.57

2.05

6.21

21.421

0.000004

D15S1007

2.64

1.63

4.28

16.093

0.000060

D16S423

2.60

1.6

4.21

15.368

0.000088

D16S3103

2.89

1.75

4.77

17.611

0.000027

  1. The table shows odds ratios (OR), adjusted for age in 6 strata and geographical location in 8 strata, of death due to bacterial invasive disease, along with lower and upper 95% confidence intervals (CI). Significance was assessed using 2 × 2 contingency table of heterozygote/homozygote vs case/control, yielding a chi-squared value (chi sq) and its associated P value. All loci comfortably exceed the experiment-wide significance threshold of 0.00037.