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Table 1 Nine microsatellites showing the strongest association between heterozygosity and mortality due to invasive bacterial disease.

From: Homozygosity and risk of childhood death due to invasive bacterial disease

Marker OR lower 95% CI upper 95% CI chi sq p value
D12S310 2.86 1.68 4.86 15.420 0.000086
D12S352 2.66 1.64 4.31 16.194 0.000057
D13158 2.67 1.66 4.3 16.496 0.000049
D14S261 3.14 1.94 5.09 21.998 0.000003
D14S275 2.59 1.59 4.22 15.034 0.000106
D14S280 3.57 2.05 6.21 21.421 0.000004
D15S1007 2.64 1.63 4.28 16.093 0.000060
D16S423 2.60 1.6 4.21 15.368 0.000088
D16S3103 2.89 1.75 4.77 17.611 0.000027
  1. The table shows odds ratios (OR), adjusted for age in 6 strata and geographical location in 8 strata, of death due to bacterial invasive disease, along with lower and upper 95% confidence intervals (CI). Significance was assessed using 2 × 2 contingency table of heterozygote/homozygote vs case/control, yielding a chi-squared value (chi sq) and its associated P value. All loci comfortably exceed the experiment-wide significance threshold of 0.00037.