Table 3 HR for acute coronary syndrome subdivided by alcohol intake and PPARγ Pro¹²Ala genotype.

PPARγ Pro¹²Ala

< 4.0

4.0 < × < 12.0

> 12.0

Men

   Pro/Pro

1^a

0.86 (0.59–1.28)

0.70 (0.50–0.98)

   Pro/Ala

1.41 (0.73–2.70)

0.90 (0.64–1.55)

0.58 (0.39–0.86)

   Ala/Ala

40.7 (27.5–60.2)

2.30 (0.29–18.5)

1.09 (0.46–2.57)

P for interaction

p < 0.0001

   Pro/Pro

1^b

0.91 (0.60–1.37)

0.69 (0.49–0.99)

   Pro/Ala

1.30 (0.67–2.55)

0.78 (0.44–1.39)

0.60 (0.39–0.90)

   Ala/Ala

25.3 (16.5–38.7)

3.18 (0.41–24.8)

1.11 (0.45–2.76)

P for interaction

p < 0.0001

Women

   Pro/Pro

1^a

0.52 (0.34–0.80)

0.52 (0.34–0.79)

   Pro/Ala

0.72 (0.41–1.27)

0.70 (0.39–1.27)

0.45 (0.23–0.88)

   Ala/Ala

0.25 (0.29–2.15)

No estimate

0.70 (0.08–6.50)

P for interaction

0.34

   Pro/Pro

1^b

0.53 (0.34–0.83)

0.51 (0.33–0.80)

   Pro/Ala

0.73 (0.40–1.31)

0.71 (0.38–1.31)

0.44 (0.22–0.88)

   Ala/Ala

0.27 (0.03–2.15)

No estimate

0.52 (0.05–5.30)

P for interaction

0.46

   Pro/Pro

1^c

0.53 (0.34–0.84)

0.52 (0.33–0.82)

   Pro/Ala

0.75 (0.41–1.35)

0.72 (0.38–1.35)

0.48 (0.24–0.86)

   Ala/Ala

0.29 (0.03–2.59)

No estimate

0.55 (0.05–5.71)

P for interaction

0.51