Figure 7
Association between IL18R1 haplotypes and CVD risk in the whole MORGAM cohorts according to BMI. Haplotypic ORs [95% confidence interval] by comparison to the reference TTIGC haplotype were adjusted for cohorts, age and gender, separately in subjects below (diamonds) and above (squares) the population-specific median of BMI. The global test of association was neither significant in the group of individuals below (χ2 = 3.767 with 6 df, p = 0.708) nor above (χ2 = 10.28 with 6 df, p = 0.113) the median of BMI. Polymorphisms are ordered according to their position on the genomic sequence.