Mosaicism for combined tetrasomy of chromosomes 8 and 18 in a dysmorphic child: A result of failed tetraploidy correction?

Table 1 Allele sizes of polymorphic chromosome 8 and18 simple tandem repeats.

UniSTS	Position (Mb from pter)	Mother (m)	Father (p)	Child	Ratio m/p peak heights
Chrom. 8:
D8S264	21	153–155	143–153	143–155	0,50
D8S1104	41	135–135	143-143	135–143	1,01
D8S268	41	260–266	264–266	260–264	1,24
D8S531	49	121–127	123-123	121–123	1,60
G08718	49	219-219	214-214	214–219	0,94
D8S517	53	251–253	255–258	251–255	1,37
D8S260	62	207–215	209–215	207–215	1,05
D8S277	65	165–173	165–169	169–173	1,18
D8S270	93	101–112	110–112	101–110	1,84
D8S1784	106	288-288	282–286	282–288	0,71
D8S550	109	194–212	210-210	210–212	0,65
					Mean 1,03
Chrom. 18:
D18S452	6	128–144	132–136	136–144	1,00
D18S53	11	165–173	165–169	169–173	1,19
D18S453	13	148–152	152-152	148–152	2,13
D18S71	13	270–278	258–276	258–278	0,55
D18S73	13	142–144	142–146	144–146	1,98
D18S1104	17	148–152	141–148	141–148	1,10
D18S1149	17	258–265	263–267	263–265	0,77
D18S869	18	186–198	186–189	186–198	1,39
D18S478	23	248–250	246-246	246–250	1,21
D18S1102	33	90–94	90–92	90–94	0,97
D18S474	47	124–126	132–138	126–138	2,68
D18S61	66	228–230	232-232	228–232	2,13
D18S1161	70	231–233	219-219	219–233	0,79
					Mean 1,24

The ratio between the maternal and paternal peak heights is given in the right column, with the geometrical means of each chromosome in bold. The names of the centromeric repeats are written in italics.

ISSN: 1471-2350