Table 3 Lipid profile according to APOE ε2/ε3/ε4 polymorphism in non-diabetic subjects without lipid-lowering therapy (n = 449)
APOE ε2/ε3/ε4 variant | Carrier E2 (n = 41) | E3/E3 (n = 333) | Carrier E4 (n = 75) | P* |
|---|---|---|---|---|
Total cholesterol (mmol/l) | 5.40 ± 1.18 | 5.73 ± 1.08 | 6.01 ± 1.10 | 0.005 |
LDL-cholesterol (mmol/l) | 3.34 ± 0.85 | 3.85 ± 0.97 | 4.03 ± 0.96 | 0.002 |
HDL-cholesterol (mmol/l) | 1.34 ± 0.37 | 1.31 ± 0.37 | 1.37 ± 0.45 | 0.457 |
Triglyceride (mmol/l) | 1.97 ± 1.36 | 1.65 ± 0.76 | 1.69 ± 0.91 | 0.562 |
Apo A-I (g/l) | 1.36 ± 0.25 | 1.34 ± 0.25 | 1.36 ± 0.25 | 0.976 |
Apo B (g/l) | 0.98 ± 0.31 | 1.16 ± 0.28 | 1.24 ± 0.28 | <0.001 |
Apo C-III (mg/dl) | 12.7 ± 5.7 | 11.0 ± 3.3 | 11.1 ± 2.9 | 0.307 |
ApoE (g/l) | 0.067 ± 0.037 | 0.042 ± 0.010 | 0.039 ± 0.011 | <0.001 |