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Table 3 CRP gene single nucleotide polymorphisms association results for postoperative plasma CRP levels following coronary artery bypass graft surgery.

From: C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery

dbSNP rs#

Minor Allele

β-Coefficient

Peak Postoperative

CRP P-value

Repeated-Measures

Postoperative CRP

P-value††

rs1572970

G

-0.124

0.709

0.180

rs876537

T

-0.107

0.041

0.272

rs876538

A

-0.143

0.606

0.155

rs2794520

T

-0.104

0.004

0.058

rs3093077

G

-0.056

0.931

0.653

rs2808630

C

-0.061

0.898

0.501

rs1205

T

-0.180

0.004

0.068

rs1130864

T

0.232

0.011

9.0 × 10-3

rs1800947

C

-0.477

2.4 × 10-4*

4.8 × 10-5*

rs1417938

C

0.242

0.007

0.006

rs3091244

C

-0.218

0.026

0.105

rs3091244

T

0.274

2.1 × 10-3

2.0 × 10-3

rs3091244

A

-0.075

0.948

0.529

rs2794521

C

-0.059

0.932

0.535

rs3093059

T

-0.067

0.986

0.584

rs3122012

C

0.253

0.009

0.007

rs2794517

A

0.057

0.962

0.555

rs3116654

C

0.014

0.567

0.903

rs3116653

G

0.249

0.008

0.005

  1. Results shown for dominant genetic model. Describes associated effect of the minor allele on postoperative CRP levels based on a Tobit regression model. The same directional effect was seen for peak postoperative CRP levels. Using rank-ordered peak postoperative CRP level adjusted for clinical covariates. ††Using repeated measures of logit-transformed postoperative CRP level in a Tobit regression model and adjusting for clinical covariates. *Below the Bonferroni adjusted level of significance for multiple comparisons.