C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery

Table 2 Candidate CRP gene single nucleotide polymorphisms.

dbSNP rs#	Chromosome Position^†	Nucleotide Position^††	Role	Minor:Major Allele	MAF (%)
rs1572970	chr1:157940209	10691	3' Downstream	G:A	0.287
rs876537	chr1:157941557	9343	3' Downstream	T:C	0.393
rs876538	chr1:157942341	8559	3' Downstream	A:G	0.186
rs2794520	chr1:157945440	5460	3' Downstream	T:C	0.337
rs3093077	chr1:157946260	4640	3' Downstream	G:T	0.071
rs2808630	chr1:157947492	3408	3' Downstream	C:T	0.265
rs1205	chr1:157948857	2043	3'UTR	T:C	0.342
rs1130864	chr1:157949715	1185	3'UTR	T:C	0.299
rs3093066	chr1:157949723	1177	3'UTR	A:C	0.009*
rs1800947	chr1:157950062	838	Coding synonymous	C:G	0.071
rs1417938	chr1:157950810	90	Intron	A:T	0.296
rs3091244	chr1:157951289	-390	Promotor	---	0.624 (C) 0.301 (T) 0.075 (A)
rs2794521	chr1:157951720	-821	Promotor	C:T	0.266
rs3093059	chr1:157951760	-861	Promotor	C:T	0.075
rs3093058	chr1:157951939	-1040	Promotor	T:A	0.006*
rs3122012	chr1:157955947	-5048	Promotor	C:T	0.295
rs2794517	chr1:157959329	-8430	Promotor	A:G	0.224
rs3116654	chr1:157962385	-11486	Promotor	C:T	0.123
rs3116653	chr1:157963534	-12635	Promotor	G:C	0.296

^†NCBI hg version 36. ^††Nucleotide position given relative to ATG start codon of the CRP gene. The alleles of the triallelic SNP rs3091244 are described in the MAF column. *Excluded from further analyses due to minor allele frequency (MAF) <1%.

ISSN: 1471-2350