C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery

Table 1 Baseline demographic and clinical characteristics of the study population (n = 604)*.

Demographic data
Age at enrollment (Yrs)	65 ± 10
Gender (Male %)	82
Race (Caucasian vs. Other %)	89
Institution A, (%)	79
Preoperative Data
Body mass index (kg/m²)	28.8 ± 4.9
History of diabetes (Types I and II) (%)	28.5
^aHistory of peripheral vascular disease (%)	9.7
^bHistory of chronic inflammation (%)	16.8
Current smoker (%)	9.3
^cPreoperative CRP level (mg/L)	1.2 [0.6–2.8]
Preoperative creatinine (mg/dL)	1.09 ± 0.30
*Preoperative Medications*
^dPreoperative steroid use (%)	2.0
Duration of statin use prior to CABG (%)
No statin use	23.1
<1 month	11.1
1–6 months	8.3
≥ 6 months	43.6
Unknown	13.9
Last statin dose administered prior to CABG (%)
<24 hours	62.1
24–72 hours	5.4
≥ 72 hours	1.3
Unknown	8.1
Preoperative aspirin use (%)	76.3
*Intraoperative Data*
^eBlood product transfusion (%)	56.3
Aortic cross clamp time (min)	73 ± 34
Cardiopulmonary bypass time (min)	98 ± 43
Number of coronary grafts (%)
1	2.8
2	13.8
3	44.9
≥ 4	38.5

*Continuous data are expressed as mean ± SD. ^aPeripheral vascular disease was defined as vascular disease of the upper or lower extremities, or thoracic or abdominal aorta by patient history. ^bChronic inflammation disease of the bowel, joints or skin by patient history. ^cCRP level expressed in median mg/L with 25^th and 75^th percentiles.^dSteroids given by any route within the last month. ^eBlood product of any kind given intraoperatively through postoperative day 2.

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