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Table 4 Hazard ratios (HR) for total and cardiac mortality according to HMOX1 genotypes and haplotypes.

From: Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study)

  HR (95% CI)
Total*
P HR (95% CI)
Cardiac*
P
A>T rs2071746     
AA 1.0reference   1.0reference  
AT1 0.99 (0.84–1.16) 0.886 1.06 (0.87–1.29) 0.569
TT1 0.96 (0.78–1.19) 0.727 0.95 (0.73–1.26) 0.734
AA vs AT or TT1 0.97 (0.80–1.18) 0.746 0.92 (0.72–1.18) 0.519
AA or AT vs TT1 0.98 (0.85–1.14) 0.818 1.03 (0.86–1.25) 0.739
VNTR S<25, L ≥ 25     
SS 1.0reference   1.0reference  
SL1 1.08 (0.84–1.40) 0.543 1.12 (0.81–1.54) 0.501
LL1 1.08 (0.84–1.39) 0.569 1.02 (0.74–1.40) 0.922
SS vs SL or LL1 1.08 (0.85–1.38) 0.536 1.06 (0.79–1.44) 0.688
SS or SL vs LL1 1.01 (0.87–1.16) 0.910 0.93 (0.77–1.11) 0.423
  1. 1Genotypes treated as categorical variables and compared to the reference category.
  2. *adjusted for age, and sex.