Skip to main content

Table 1 Baseline characteristics and risk factors in patients with angiographically proven CAD, and previous MI as compared to controls without CAD.

From: Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study)

  

Controls

CAD

p

CAD and MI

p

 

Male

(n = 360)

(n = 1891)

 

(n = 1060)

 
 

Female

(n = 333)

(n = 635)

 

(n = 279)

 

Age (years) means ± SD

Male

55 ± 12

63 ± 10

 

63 ± 10

 
 

Female

62 ± 10

66 ± 10

<0.0011

65 ± 10

<0.0011

Body mass index (kg/m2) means ± SD

Male

27 ± 4

28 ± 4

 

27 ± 4

 
 

Female

27 ± 5

27 ± 5

n.s.2

27 ± 5

n.s.2

Smoker (former and current)

Male

239 (66%)

1487 (78%)

 

867 (82%)

 
 

Female

100 (30%)

253 (39%)

<0.0014

145 (51%)

<0.0014

Diabetes mellitus

Male

63 (17%)

653 (34%)

 

374 (35%)

 
 

Female

66 (20%)

253 (39%)

<0.0014

120 (42%)

<0.0014

Systemic Hypertension

Male

212 (58%)

1399 (74%)

 

736 (69%)

 
 

Female

228 (69%)

519 (81%)

0.0024

220(77%)

n.s.4

Fasting blood glucose (mmol/L) means ± SD

Male

5,89 ± 1,67

6,39 ± 1,89

 

6,34 ± 1,83

 
 

Female

5,78 ± 1,34

6,6 ± 2,44

<0.0012

6,67 ± 2,5

<0.0012

LDL-C(mmol/L) means ± SD

Male

3,02 ± 0,8

2,92 ± 0,85

 

2,84 ± 0,83

 
 

Female

3,2 ± 0,8

3,2 ± 1,01

0.0023

3,05 ± 1,01

n.s.3

HDL-C (mmol/L) means ± SD

Male

1,03 ± 0,28

0,93 ± 0,23

 

0,9 ± 0,23

 
 

Female

1,19 ± 0,31

1,09 ± 0,28

<0.0013

1,03 ± 0,28

<0.0013

Bilirubin (μmol/L) means ± SD

Male

13,17 ± 7,53

11,46 ± 6,33

 

10.95 ± 5.82

 
 

Female

9.58 ± 4,62

8,89 ± 6,16

<0.0012

8,38 ± 4,10

<0.0012

Iron (μmol/L)

Male

19,52 ± 8.06

16,66 ± 6,98

 

16,12 ± 6,98

 
 

Female

17,19 ± 6,09

14,69 ± 5,91

<0.0012

13,97 ± 5,91

<0.0012

Triglycerides (mmol/L)

median (25th and 75th percentile)

Male

1,64

(1,16–2,4)

1,69

(1,26–2,27)

 

1,7

(1,26–2,25)

 
 

Female

1,44

(1,04–2,01)

1,73

(1,3–2,34)

<0.0123

1,75

(1,31–2,46)

n.s.3

  1. 1analysis of variance adjusted for gender only
  2. 2analysis of variance adjusted for age and gender
  3. 3analysis of variance additionally adjusted for use of lipid-lowering drugs
  4. 4logistic regression, adjusted for age and gender