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Table 3 Odds ratios (OR) and 95% confidence intervals (CI) for the association between mitochondrial haplogroup and CAD and Valvular Heart Disease, respectively.

From: Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study

 

Haplogroup

OR* (95% CI)

p-value

aOR† (95% CI)

p-value

Coronary artery disease

     
 

H

1 (ref)

 

1 (ref)

 
 

U

1.06 (0.69–1.61)

0.791

1.18 (0.72–1.93)

0.504

 

J

0.92 (0.58–1.47)

0.738

1.09 (0.63–1.89)

0.766

 

T

2.36 (1.52–3.65)

< 0.0005‡

2.33 (1.37–3.98)

0.002‡

Valvular Heart disease

     
 

H

1 (ref)

   
 

U

1.05 (0.50–2.17)

0.903

  
 

J

0.96 (0.44–2.14)

0.930

  
 

T

1.24 (0.52–2.96)

0.626

  
  1. *Adjusted for age and sex (CAD n = 382, Valvular heart disease n = 93, controls n = 1203); †adjusted for age, sex, smoking, hypertension, and body mass index (CAD n = 345, controls n = 1095); ‡Bonferroni-corrected statistical significance: p < 0.05/3 × 2 = < 0.008.
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BMC Medical Genetics

ISSN: 1471-2350

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