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Table 2 Association analysis of the ten tag SNPs in GD patients and control subjects

From: Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence

 

Allele

Genotype of case

Genotype of control

Allele comparison

Genotype comparison

Rs number

1/2

11

12

22

11

12

22

OR (95% CI)

P value

P value

rs2053044

G/A

220

167

32

375

251

52

0.932(0.768–1.131)

0.48

0.63

rs17108803

T/G

390

33

2

596

74

4

1.420(0.960–2.120)

0.08

0.21

rs12654778

G/A

161

196

68

254

316

112

1.022(0.858–1.219)

0.80

0.97

-332

G/A

410

15

1

645

28

0

1.043(0.568–1.918)

0.89

0.41

rs1042713

A/G

170

179

76

248

301

123

1.076(0.903–1.283)

0.41

0.58

rs1042714

C/G

358

63

3

592

88

5

0.870(0.631–1.199)

0.39

0.64

rs1042717

A/G

199

168

45

312

276

83

1.077(0.894–1.298)

0.43

0.73

rs1042719

G/C

137

216

66

213

318

139

1.128(0.947–1.343)

0.18

0.11

rs3730182

T/C

401

18

0

647

22

1

0.831(0.448–1.540)

0.56

0.64

rs1042720

A/G

155

208

56

280

293

94

0.913(0.763–1.091)

0.32

0.17