Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence

Table 1 Fifteen SNPs in the ADRB2 gene identified from 24 GD patients and 24 control subjects

Rs number	Position in ADRB2	Chromosome position	Alleles	HWpval	MAF
rs17108803	- 839	148185749	T:G	1.00	0.032
rs12654778	- 654	148185934	G:A	0.13	0.415
rs11168070	- 468	148186120	C:G	1.00	0.062
rs11959427	- 367	148186221	T:C	1.00	0.062
-332	- 332	148186256	G:A	1.00	0.042
rs1042711	- 47	148186541	T:C	1.00	0.052
rs1801704	- 20	148186568	T:C	1.00	0.052
rs1042713	+ 46	148186633	A:G	0.88	0.365
rs1042714	+ 79	148186666	C:G	1.00	0.052
rs1042717	+ 252	148186839	G:A	0.13	0.302
rs1042718	+ 523	148187110	C:A	0.13	0.302
rs1042719	+ 1053	148187640	G:C	0.60	0.389
rs3730182	+ 1179	148187766	T:C	1.00	0.011
rs1042720	+ 1239	148187826	A:G	0.58	0.352

SNP positions in the ADRB2 gene were numbered upstream (+) or downstream (-) from the ADRB2 transcription initiation site. Chromosome positions were referred to the sequence of NCBI database (built 35). SNP, single nucleotide polymorphism; Hwpval, Hardy-Weinberg equilibrium p value; MAF, minor allele frequency.

ISSN: 1471-2350