Table 1 Clinical features of obese children with MC4R mutations
Mutation (sex) | S127L (M) | S127L (F) | S127L (F) | Q307X (F) | Y332H (F) |
|---|---|---|---|---|---|
Age (years) | 8 | 10 | 10 | 3 | 11 |
Age at obesity onset (years) | 2 | 4 | 7 | 1 | 3 |
z-score BMI | 3.2 | 3.6 | 4.0 | 5.1 | 4.0 |
Height-sds | 2.0 | 2.1 | 2.4 | 2.0 | 2.2 |