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Table 5 Association of CRP haplotypes with COPD and ln(CRP)

From: IL6 and CRPhaplotypes are associated with COPD risk and systemic inflammation: a case-control study

 

COPD*

 

Ln(CRP) †

 

Haplotype

OR (95%CI)

P-value

Coefficient ± SE

P-value

H1

0.85 (0.57–1.27)

0.42

-0.33 ± 0.13

0.01

H2

0.86 (0.64–1.16)

0.43

-0.13 ± 0.13

0.34

H3

1.64 (0.83–3.27)

0.16

-0.58 ± 0.20

0.004

H4

REFERENT

 

REFERENT

 

H5

1.35 (0.69–2.65)

0.38

-0.02 ± 0.21

0.92

Others‡

2.91 (0.77–0.98)

0.12

0.66 ± 0.27

0.01

  1. * Logistic regression analyses were adjusted for age, sex and tobacco consumption (pack-years smoked).
  2. † Linear regression analyses were adjusted for age, sex, BMI and 6MWD.
  3. ‡ Rare haplotypes (frequency < 2.5%) were coded in aggregate as "others"