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Table 5 Association of CRP haplotypes with COPD and ln(CRP)

From: IL6 and CRPhaplotypes are associated with COPD risk and systemic inflammation: a case-control study

  COPD*   Ln(CRP) †  
Haplotype OR (95%CI) P-value Coefficient ± SE P-value
H1 0.85 (0.57–1.27) 0.42 -0.33 ± 0.13 0.01
H2 0.86 (0.64–1.16) 0.43 -0.13 ± 0.13 0.34
H3 1.64 (0.83–3.27) 0.16 -0.58 ± 0.20 0.004
H4 REFERENT   REFERENT  
H5 1.35 (0.69–2.65) 0.38 -0.02 ± 0.21 0.92
Others‡ 2.91 (0.77–0.98) 0.12 0.66 ± 0.27 0.01
  1. * Logistic regression analyses were adjusted for age, sex and tobacco consumption (pack-years smoked).
  2. † Linear regression analyses were adjusted for age, sex, BMI and 6MWD.
  3. ‡ Rare haplotypes (frequency < 2.5%) were coded in aggregate as "others"