PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism

Table 1 PRNP gene sequence variation in vCJD cases

Codon	Number Tested	Genotype Data
129 (Met/Val)	147	All cases MM
	4 (blood transfusion associated infections)	MM (n = 3) MV (n = 1)*
	2 (appendix tissue)	VV (n = 2)**
202 (Asp/Asp)	118	DD (n = 2)
219 (Glu/Lys)	118	EK (n = 2)
24 bp deletion	118	DelR34 (n = 1)

ISSN: 1471-2350