From: Use of supplementary phenotype to identify additional rheumatoid arthritis loci in a linkage analysis of 342 UK affected sibling pair families
Size of sibling pair
No. of families
No. of subjects
Mean onset age (years ± standard error)
2
306
612
-
3
31
93
4
12
5
1
6
All
342
728
41.63 ± 0.51
Females
537
41.44 ± 0.61
Males
191
42.17 ± 0.89