Figure 2From: Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients Alignment of the primary sequence of melusin CHORD 1 domain in a number of mammalian species indicates the high degree of conservation of the gene. The characteristic C (cysteine) and H (histidine) signature are highlighted. The position of the missense mutation detected in HCM patient causing His-13 > Tyr amino acid change is indicated by the arrowhead. (*) conserved residues (:) conserved substitutions.Back to article page