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Table 2 Basic characteristics of subjects in hypertensives and normotensives

From: Genetic variation of NEDD4L is associated with essential hypertension in female Kazakh general population: a case-control study

 

Total

Male

Female

 

Control

(n = 500)

Case

(n = 383)

P

Control

(n = 204)

Case

(n = 171)

P

Control

(n = 296)

Case

(n = 212)

P

Age

(year)

42.04 ± 7.35

46.23 ± 7.63

< 0.001*

42.24 ± 7.48

46.11 ± 7.97

< 0.001*

41.90 ± 7.28

46.34 ± 7.37

< 0.001*

BMI

(kg/m2)

25.27 ± 3.55

28.14 ± 4.50

< 0.001*

25.39 ± 3.23

28.52 ± 4.22

< 0.001*

25.18 ± 3.76

27.83 ± 4.70

< 0.001*

SBP

(mmHg)

117.78 ± 11.11

150.60 ± 25.90

< 0.001*

119.43 ± 10.58

149.28 ± 25.67

< 0.001*

116.65 ± 11.34

151.67 ± 26.11

< 0.001*

DBP

(mmHg)

78.28 ± 7.53

96.88 ± 10.92

< 0.001*

80.29 ± 6.24

97.03 ± 10.45

< 0.001*

76.88 ± 8.04

96.76 ± 11.32

< 0.001*

TC

(mmol/L)

4.88 ± 1.00

5.14 ± 1.05

< 0.001*

5.09 ± 1.07

5.26 ± 1.03

0.111

4.84 ± 0.93

5.05 ± 1.06

0.001*

HDL

(mmol/L)

1.47 ± 0.38

1.44 ± 0.39

0.244

1.31 ± 0.34

1.27 ± 0.31

0.244

1.58 ± 0.37

1.58 ± 0.40

0.927

TG

(mmol/L)

1.00 ± 0.60

1.23 ± 0.74

< 0.001*

1.23 ± 0.75

1.53 ± 0.91

0.001*

0.85 ± 0.43

0.99 ± 0.46

0.001*

FBG

(mmol/L)

4.83 ± 0.65

5.08 ± 1.35

0.001*

4.95 ± 0.63

5.21 ± 1.59

0.050

4.75 ± 0.65

4.98 ± 1.12

0.008*

UNa rate (uM/min)

163.78 ± 85.55

171.14 ± 87.57

0.260

182.64 ± 93.98

190.79 ± 88.33

0.439

150.31 ± 76.39

155.27 ± 83.90

0.536

Pl Na (mmol/L)

144.57 ± 8.98

144.74 ± 8.75

0.785

145.91 ± 9.32

145.09 ± 7.34

0.353

143.67 ± 8.66

144.45 ± 9.74

0.338

Life style

         

Smoking

(%)

22.8

24.3

0.606

55.4

52.6

0.593

0.3

1.4

0.176

Drinking

(%)

21.6

21.1

0.871

52.0

44.4

0.147

0.7

2.4

0.109

Present illness

         

Overweight (%)

49.9

74.3

0.000*

53.1

79.8

0.000*

47.7

69.8

0.000*

Dyslipidemia (%)

38.9

53.4

0.000*

60.0

68.8

0.078

24.7

41.0

0.000*

Hyperglycemia (%)

16.7

25.2

0.002*

15.5

23.5

0.057

17.4

26.6

0.014*

  1. BMI; body mass index, SBP; systolic blood pressure, DBP; diastolic blood pressure, TC; total cholesterol, HDL-c; high-density lipoprotein cholesterol. TG; triglyceride, FBG; fasting blood glucose, Una rate; urinary Na excretion rate, PlNa; plasma Na. Values are mean ± SD or percentage. P < 0.05 was considered significant. The differences between case and control group were performed by t-test or X2 test.
  2. * P < 0.05