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Table 2 Haplotype association analysis between DYRK1A gene and AD

From: DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort

Haplotype block

Haplotype frequency

AD, control frequency

P value

ATACCG

0.329

0.347, 0.314

0.07

ACGCCA

0.202

0.190, 0.211

0.18

ATATCG

0.154

0.152, 0.155

0.82

ATACTG

0.115

0.112, 0.118

0.61

GTGCCA

0.109

0.107, 0.112

0.65

ATACCA

0.074

0.069, 0.077

0.43

  1. Haplotype block consists of SNPs: rs11701483, rs2835740, rs1137600, rs2835761, rs2835762 and rs2154545. Rare haplotypes (total frequency < 0.05) were excluded from the analysis. P-values were not corrected for multiple comparisons.
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BMC Medical Genetics

ISSN: 1471-2350

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