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Table 2 SNPs associated with asthma or atopy with a FDR of 5% in the pooling-based GWA

From: A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS)

SNP

Chromosome

Position

Comparison

p value

fAco-fAca

Region

Saturation

rs2501618

1

178225432

Atopy vs. controls

1.26 × 10-7

0.26

CEP350

No

rs4952590

2

42130425

Atopy vs. controls

4.63 × 10-7

0.19

SGK493 (LOC91461)

Yes

rs7629719

3

131642624

Atopy-Asthma vs. controls

1.11 × 10-7

0.21

COL29A1 (COL6A5)

Yes

rs9292961

5

20975886

Atopy vs. controls

5.38 × 10-7

0.3

Segmental Duplications

No

rs9376221

6

137034072

Atopy vs. controls

3.94 × 10-7

0.25

MAP3K5 (ASK1)

Yes

rs7843085

8

33235086

Atopy vs. controls

3.93 × 10-7

0.26

NT_007995.50

Yes

rs13273924

8

33246541

Atopy vs. controls

7.56 × 10-7

0.26

NT_007995.50

Yes

rs2330183

21

45777720

Atopy vs. controls

1.59 × 10-7

0.28

SLC19A1

Yes

  1. fAco (allele frequency in controls); fAca (allele frequency in cases); CEP350: centrosomal protein 350 kDa; SGK493: protein kinase-like protein SgK493; COL29A1: collagen, type XXIX, alpha 1; MAP3K5: mitogen-activated protein kinase kinase kinase 5; ASK1: apoptosis signal-regulating kinase 1; SLC19A1: solute carrier family 19 (folate transporter), member 1