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Table 2 Comparison of prediction error between MDR and PLR.

From: Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene Interaction in a case-control study

Model

MDR

PLR

Model1

0.077 (0.014)

0.077 (0.013)

Model2

0.131 (0.016)

0.132 (0.015)

Model3

0.123 (0.015)

0.123 (0.015)

Model4

0.379 (0.038)

0.407 (0.047)

Model5

0.331 (0.027)

0.345 (0.026)

Model6

0.413 (0.049)

0.457 (0.062)

Model7

0.383 (0.033)

0.460 (0.065)

Model8

0.386 (0.032)

0.485 (0.038)

Model9

0.382 (0.036)

0.437 (0.048)

  1. The prediction error of MDR and PLR for 2-way interaction models when P(A) = P(B) = 0.5, where A and B are the minor alleles of SNP1 and SNP2 respectively.
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BMC Medical Genetics

ISSN: 1471-2350

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