Table 1 Allele and Genotype frequencies for CYP2C8, CYP2C9 and CYP2C19 alleles observed in the Ghanaian population (%, 95% CI in parenthesis)
From: Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population
| Â | CYP2C8*2 | CYP2C9*11 | CYP2C19*2 |
|---|---|---|---|
Total no. genotyped | 203 | 195 | 169 |
Major allele homozygous | 139 (68, 62.0 - 74.86) | 190 (97.5, 95.22 - 99.66) | 152 (90, 85.48 - 94.52) |
Heterozygous | 59 (29, 22.8 - 35.31) | 4 (2, 0.06 - 4.04) | 14 (8, 3.91, 12.09) |
Minor allele homozygous | 5 (3, 0.33 - 4.59) | 1 (0.5, -0.49 - 1.51) | 3 (2, -0.21, 3.77) |
Major allele frequency | 83 (79.35 - 86.65) | 98 (96.61- 99.39) | 94 (91.47- 96.53) |
Minor allele frequency | 17(13.35 - 20.65) | 2 (0.61, 3.39) | 6 (3.47, 8.53) |