Table 4 Associations between haplotypes in PFH11, DPP10, HLA-G and asthma-related phenotypes, adjusted for age, gender, height, weight, BMI and smoking status.

rs2247119

rs1046295

SPT^c

T

G

47.9

46.5

1

C

A

38.9

39.7

1.06 (0.81-1.40)

0.67

T

A

11.3

9.6

0.85 (0.60-1.19)

0.34

C

G

2.0

4.1

2.05 (1.11-3.81)

0.023

SPT + Asthma ^d

T

G

48.4

47.7

1

C

A

38.5

39.0

1.04 (0.75-1.44)

0.80

T

A

10.9

9.6

0.88 (0.59-1.32)

0.55

C

G

2.1

3.7

1.59 (0.78-3.25)

0.20

rs10192393

rs1430092

MTCH Challenge^e

T

C

88.2

84.4

1

T

T

7.9

8.7

1.25 (0.86-1.82)

0.24

C

C

3.9

6.8

1.99 (1.25-3.17)

0.0040*

MTCH Challenge + Asthma ^r

T

C

88.1

83.2

1

T

T

8.1

9.8

1.33 (0.88-2.01)

0.17

C

C

3.8

7.0

2.15 (1.28-3.62)

0.0041*

rs1430090

rs6737251

rs7580359

MTCH Challenge

G

C

C

38.7

39.2

1

T

C

C

34.6

35.5

0.98 (0.74-1.31)

0.90

T

T

T

25.3

23.6

0.88 (0.66-1.16)

0.36

G

C

T

1.4

1.7

1.23 (0.54-2.78)

0.62

rs1632949

rs1736935

MTCH Challenge

A

T

43.2

38.8

1

G

C

31.5

32.1

1.15 (0.93-1.44)

0.20

A

C

25.4

29.0

1.24 (0.99-1.56)

0.060

MTCH Challenge + Asthma

A

T

42.6

37.5

1

G

C

32.2

30.8

1.11 (0.87-1.43)

0.40

A

C

25.2

31.7

1.40 (1.09-1.80)

0.0086