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Table 4 Models of inheritance for the CTLA4 rs3087243 and PTPN22 rs2476601 associations in AAV

From: Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis

 

Pvalue of indicated model

 

Co-dominant

Dominant

Over-dominant

Recessive

Log-additive

CTLA4

rs3087243

0.02

0.03

0.92

0.02

5.8 × 10-3

PTPN22

rs2476601

8.5 × 10-4

1.8 × 10-4

4.3 × 10-4

0.26

2.0 × 10-4