Skip to main content

Table 3 Meta-analysis for PTPN22 rs2476601 in AAV

From: Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis

 

Controls

this study//Jagiello1

AAV cases

this study//Jagiello1

 

n

7412//399

Frequency

n

626//199

Frequency

Combined

P value

GG

6044//323

0.82//0.81

471//142

0.75//0.71

 

GA

1298//72

0.18//0.18

146//52

0.23//0.26

 

AA

70//4

0.01//0.01

9//5

0.01//0.03

2.2 × 10-6 *

G

13386//718

0.90//0.90

1088//336

0.86//0.84

 

A

1438//80

0.10//0.10

164//62

0.13//0.16

4.2 × 10-7 ** §

  1. 1 Data from Jagiello et al [11]
  2. * P value calculated by χ2 test on 3 × 2 contingency table
  3. ** P value calculated by χ2 test on 2 × 2 contingency table
  4. § OR for minor allele = 1.48