From: Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis
 | Controls this study//Jagiello1 | AAV cases this study//Jagiello1 | |||
---|---|---|---|---|---|
 | n 7412//399 | Frequency | n 626//199 | Frequency | Combined P value |
GG | 6044//323 | 0.82//0.81 | 471//142 | 0.75//0.71 | Â |
GA | 1298//72 | 0.18//0.18 | 146//52 | 0.23//0.26 | Â |
AA | 70//4 | 0.01//0.01 | 9//5 | 0.01//0.03 | 2.2 × 10-6 * |
G | 13386//718 | 0.90//0.90 | 1088//336 | 0.86//0.84 | Â |
A | 1438//80 | 0.10//0.10 | 164//62 | 0.13//0.16 | 4.2 × 10-7 ** § |