Table 1 Clinical Characteristics of the Affected Individuals
CPVT (Group A) | Resting VPCs (Group B) | P | ||
|---|---|---|---|---|
n | 16 | 17 | NS | |
Females, n (%) | 6 (38) | 13 (77) | <0.05 | |
Age at onset, y | 25 ± 16 (10–64) | 27 ± 18 (5–51) | NS | |
Syncope, n (%) | 14 (88) | 9 (53) | NS | |
Heart rate, bpm | 60 ± 15 (38–98) | 73 ± 20 (42–99) | NS | |
QT, ms | 430 ± 55 (350–550) | 405 ± 55 (320–490) | NS | |
QTc, ms | 420 ± 25 (380–440) | 430 ± 30 (380–450) | NS | |
Exercise stress test | Threshold heart rate, bmp | 127 ± 30 (87–184) | - | - |
Consecutive VPCs, n | 4 ± 6 (0–15) | 1 ± 1 (0–5) | NS | |
24 hour ECG recording | VPCs, n | 560 ± 800 (0–2670) | 13800 ± 11100 (224 – 33200) | <0.001 |
Consecutive VPCs, n | 1 ± 1 (0–3) | 5 ± 6 (0–24) | <0.01 | |
Familial occurrence, n (%) | 6 (38) | 7 (41) | NS | |
Affected relatives, n (%) | 12 (16) | 26 (17) | NS | |
SD in family, n (%) | 5 (31) | 3 (18) | NS |