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Table 1 Clinical Characteristics of the Affected Individuals

From: Search for cardiac calcium cycling gene mutations in familial ventricular arrhythmias resembling catecholaminergic polymorphic ventricular tachycardia

   CPVT (Group A) Resting VPCs (Group B) P
n   16 17 NS
Females, n (%)   6 (38) 13 (77) <0.05
Age at onset, y   25 ± 16 (10–64) 27 ± 18 (5–51) NS
Syncope, n (%)   14 (88) 9 (53) NS
Heart rate, bpm   60 ± 15 (38–98) 73 ± 20 (42–99) NS
QT, ms   430 ± 55 (350–550) 405 ± 55 (320–490) NS
QTc, ms   420 ± 25 (380–440) 430 ± 30 (380–450) NS
Exercise stress test Threshold heart rate, bmp 127 ± 30 (87–184) - -
  Consecutive VPCs, n 4 ± 6 (0–15) 1 ± 1 (0–5) NS
24 hour ECG recording VPCs, n 560 ± 800 (0–2670) 13800 ± 11100 (224 – 33200) <0.001
  Consecutive VPCs, n 1 ± 1 (0–3) 5 ± 6 (0–24) <0.01
Familial occurrence, n (%)   6 (38) 7 (41) NS
Affected relatives, n (%)   12 (16) 26 (17) NS
SD in family, n (%)   5 (31) 3 (18) NS
  1. Values are mean ± SD (range). VPCs, ventricular premature complexes; ECG, electrocardiogram; SD, history of sudden death at age ≤ 40 in the first or second degree relatives; NS, Statistically non-significant.