Table 2 Frequency of PIN1 haplotypes in LOAD, EOAD and FTD patients compared with the control group
Haplotype * | Controls (%) | All patients (LOAD, EOAD and FTD) together (%) | p value for all patients together vs controls | LOAD (%) | p value for LOAD vs controls | EOAD (%) | p value for EOAD vs controls | FTD (%) | p value for FTD vs controls |
|---|---|---|---|---|---|---|---|---|---|
CGTGCA | 68.7 | 66.1 | 0.510 | 67.1 | 0.717 | 64.3 | 0.438 | 65.8 | 0.588 |
GGCGCG | 17.8 | 18.4 | 0.844 | 17.6 | 0.951 | 18.4 | 0.902 | 20.2 | 0.599 |
CCCGCG | 8.7 | 11.3 | 0.307 | 9.9 | 0.654 | 15.3 | 0.080 | 10.5 | 0.581 |
CGTGCG | 1.0 | 1.2 | 0.835 | 0.9 | 0.948 | 0.0 | 0.333 | 2.7 | 0.253 |
CCCGTA | 1.0 | 1.2 | 0.838 | 2.3 | 0.294 | 0.0 | 0.329 | 0.0 | 0.291 |
GGCGCA | 1.0 | 0.5 | 0.458 | 0.0 | 0.149 | 1.0 | 0.962 | 0.9 | 0.942 |
CCCGTG | 0.9 | 0.5 | 0.459 | 0.9 | 0.954 | 0.0 | 0.331 | 0.0 | 0.296 |
CGCACA | 0.5 | 0.5 | 0.972 | 0.5 | 0.963 | 1.0 | 0.585 | 0.0 | 0.458 |
CCCGCA | 0.5 | 0.0 | 0.151 | 0.0 | 0.303 | 0.0 | 0.495 | 0.0 | 0.463 |
CGCGCA | 0.0 | 0.2 | 0.488 | 0.5 | 0.332 | 0.0 | - | 0.0 | - |
GCCGCG | 0.0 | 0.2 | 0.488 | 0.5 | 0.332 | 0.0 | - | 0.0 | - |