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Table 1 Variations found in DHPLC screening.

From: ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

SNP CHD chromosomes Non-CHD chromosomes
c.A453G (exon 4)(rs16939660) 1/166 (0,6%) 0/200 (0%)
rs35667670 intron 2 3/146 (2%) 3/92 (3,26%)
c.160-422G > A (intron 3) 80/158 (50,63%) 41/88 (46,6%)
c.25-422G > C (intron 3) 1/166 (0,6%) 2/100 (2%)
c.116+613G > T (intron 5) 63/156 (40,38%) 44/94 (46,80%)
c.92+742_93+742insA (intron 6) 1/166 (0,6%) 0/100 (0%)
rs3784259 (intron 8) 75/158 (47,48%) 46/92 (50%)
  1. In this study we found 5 intronic alterations and one polymorphism (c.A453G) in ALDH1A2 exon 4.