Table 2 Gene location and minor allele frequencies of PLAUR SNPs genotyped

1

rs4803648

3'UTR

A/T

LDtSNP

0.20

0.19

0.19

2

rs4802189

3'UTR

A/C

LDtSNP

0.16

0.16

0.15

3

rs4251953

3'UTR/intron

G/A

LDtSNP

0.04

0.05

0.04

4

rs4251938

3'UTR/intron

A/G

LDtSNP

0.12

0.12

0.11

5

rs4251923

3'UTR/intron

G/A

3'UTR

0.04

0.02

0.04

6

rs4760

Exon 7

T/C

Pro317/272Leu, LDtSNP

0.16

0.17

0.15

7

rs2302524

Exon 6

T/C

Lys220/175Arg LDtSNP

0.16

0.16

0.15

8

rs4251864

Intron 3

T/C

LDtSNP

0.09

0.09

0.08

9

rs2239372

Intron 3

G/A

LDtSNP

0.50

0.48

0.51

10

rs2283628

Intron 3

T/C

LDtSNP

0.18

0.18

0.18

11

rs4251846

Intron 3

C/T

LDtSNP

0.12

0.11

0.13

12

rs2239374

Intron 3

C/T

LDtSNP

0.18

0.19

0.17

13

rs2286960

Intron 1

C/T

LDtSNP

0.24

0.28

0.23

14

rs4251805

5'UTR-119

G/A

Promoter

0.04

0.03

0.04

15

rs344781

5'UTR-466

T/C

Promoter

0.23

0.29

0.29

16

rs2356338

5'UTR-649

G/T

Promoter

0.28

0.29

0.29

17

rs344780

5'UTR-3545

C/T

Promoter

0.23

0.20

0.22

18

rs344779

5'UTR-3666

G/T

LDtSNP

0.39

0.40

0.37

19

rs8113334

5'UTR-6873

T/C

LDtSNP

0.19

0.19

0.19

20

rs4493171

5'UTR-10534

C/T

LDtSNP

0.22

0.19

0.23

21

rs7259340

5'UTR-12331

C/A

LDtSNP

0.36

0.37

0.34

22

rs11668247

5'UTR-20040

C/T

LDtSNP

0.39

0.43

0.37

23

rs346043

5'UTR-20459

T/C

LDtSNP

0.26

0.26

0.27

24

rs740587

5'UTR-22346

T/C

LDtSNP

0.45

0.49

0.42

25

rs346054

5'UTR-30147

C/G

LDtSNP

0.45

0.47

0.46

Number

992

176

599