Table 2 General clinical parameters of IgAN patients with different c.-347-190G>A genotypes of C1GALT1C1 gene
Males | Females | ||||
|---|---|---|---|---|---|
G | A | GG | GA | AA | |
Age, years | 29.6 ± 11.7 | 30.8 ± 11.7 | 33.0 ± 10.7 | 32.6 ± 11.5 | 31.8 ± 9.9 |
Courses of diseases, months* | 5.0(16.2) | 4.0(14.7) | 6.0(22.0) | 6.0(22.3) | 6.0(15.0) |
Incidence of gross hematuria, % | 27.1 | 27.8 | 44.3 | 44.9 | 35.1 |
Incidence of hypertension, % | 51.2 | 48.8 | 25.0 | 36.4 | 33.3 |
Systolic blood pressure, mmHg | 129 ± 20 | 128 ± 20 | 117 ± 19 | 122 ± 23 | 118 ± 19 |
Diastolic blood pressure, mmHg | 82 ± 15 | 81 ± 14 | 74 ± 14 | 78 ± 14 | 76 ± 14 |
Urinary protein excretion, g/day | 2.76 ± 3.44 | 2.14 ± 2.18 | 2.19 ± 3.26 | 2.00 ± 2.64 | 2.11 ± 2.84 |
Serum creatinine, μmol/l | 123.3 ± 95.1 | 140.6 ± 170.6 | 89.4 ± 89.9 | 83.5 ± 40.1 | 86.0 ± 81.0 |
eGFR#, ml/min/1.73 m2 | 67.7 ± 35.0 | 62.3 ± 29.9 | 87.1 ± 31.6 | 86.3 ± 30.3 | 90.7 ± 35.2 |
Serum albumin, g/l | 37.8 ± 6.9 | 39.0 ± 7.0 | 37.4 ± 6.2 | 38.2 ± 5.3 | 35.8 ± 7.7 |
Serum IgA, g/l | 2.94 ± 1.27 | 3.02 ± 1.04 | 3.00 ± 1.06 | 3.06 ± 1.35 | 2.93 ± 1.23 |