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Table 4 Selected baseline characteristics including age (years), body mass index (kg/m2), lipids, lipoproteins (mg/dL and mmol/L) apolipoproteins (mg/dL) and presence or absence of ABCA1 splice variants of the low HDL pedigree

From: Multiple splice defects in ABCA1cause low HDL-C in a family with Hypoalphalipoproteinemia and premature coronary disease

Relative

Age

BMI

TC

TG

HDL

LDL

ApoAI

ApoB

IVS7+6c>t

IVS31-1g>c

Father (D1)

65

38.3

189

245

35

105

149

110

Yes

No

(mmol/L)

  

4.90

2.77

0.91

2.72

    

Mother (D2)

63

30.9

155

293

31

65

139

87

No

Yes

(mmol/L)

  

4.01

3.31

0.80

1.68

    

Proband (D3)

41

28.2

101

56

12

65

70

59

Yes

Yes

(mmol/L)

  

2.62

0.63

0.31

1.68

    

Sister (D4)

37

29.3

149

70

22

113

73

90

Yes

Yes

(mmol/L)

  

3.86

0.79

0.57

2.93

    

Brother (D5)

43

34.6

159

176

24

100

109

94

No

Yes

(mmol/L)

  

4.12

1.99

0.62

2.59

    

Daughter (D6)

16

 

74

42

35

31

100

25

No

Yes

(mmol/L)

  

1.92

0.47

0.91

0.80

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