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Fig. 2 | BMC Medical Genetics

Fig. 2

From: Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania

Fig. 2

Characterization of SCD gene function and exome map from the targeted next generation sequencing: This included the exon and full regions for validated and novel fetal hemoglobin-associated loci, including B-cell lymphoma/leukemia 11A (BCL11A), proto-oncogene, transcription factor (MYB), Homeobox A9 (HOXA9), Hemoglobin subunit beta (HBB), hemoglobin subunit gamma 1 (HBG1), hemoglobin subunit gamma 2 (HBG2), chromodomain helicase DNA binding protein 4 (CHD4), Kruppel like factor 1 (KLF1), methyl-CpG binding domain protein 3 (MBD3), zinc finger and BTB domain containing 7A (ZBTB7A), Peptidoglycan recognition protein 1 (PGLYRP1) on chromosomes 2, 6, 7, 11, 12 and 19, respectively. a gene functions from patients with high HbF levels and b gene functions from patients with low HbF levels

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BMC Medical Genetics

ISSN: 1471-2350

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