Table 2 Transmission disequilibrium test (TDT) of the single-nucleotide polymorphisms (SNPs) in nonsyndromic cleft lip with or without cleft palate (NSCL ± P) trios
SNP | MAF | Number of families | T/NT | Z score | p value |
|---|---|---|---|---|---|
rs16260 | 0.295 | 135 | 86/49 | 1.00 | 0.31 |
rs9929218 | 0.271 | 133 | 78/55 | -0.46 | 0.64 |
rs7186053 | 0.329 | 134 | 84/50 | -0.98 | 0.32 |
rs4783573 | 0.523 | 146 | 103/43 | -1.39 | 0.16 |
rs7591 | 0.543 | 154 | 121/33 | 0.55 | 0.58 |
rs7210356 | 0.081 | 54 | 34/20 | -2.47 | 0.01 |
rs4791171 | 0.616 | 139 | 118/21 | 0.36 | 0.71 |
rs11079571 | 0.215 | 99 | 50/49 | -1.68 | 0.09 |
rs3923087 | 0.606 | 136 | 116/20 | 0.00 | 1.00 |